Botulinum Neurotoxins: APA Citation Guide
This mind map provides a structured guide to APA citations for significant research on botulinum neurotoxins. It details essential studies, their primary focus, and complete publication information, including journal, volume, pages, and Digital Object Identifiers (DOIs). This resource assists researchers and students in accurately referencing foundational literature, ensuring academic integrity and facilitating easy access to critical scientific contributions in the field of neurotoxin research.
Key Takeaways
APA citations are essential for accurately referencing botulinum neurotoxin research.
Key studies cover genetic, structural, mechanistic, and pharmacological insights.
Proper referencing includes authors, publication year, article title, journal, and DOI.
Seminal works detail botulinum toxin's action, biology, and therapeutic evolution.
Understanding these citations helps navigate foundational literature on neurotoxins.
What insights did Rossetto, Pirazzini, & Montecucco (2014) provide on botulinum neurotoxins?
Rossetto, Pirazzini, and Montecucco's 2014 publication offered crucial insights into botulinum neurotoxins, focusing on their fundamental genetic makeup, intricate structural characteristics, and precise mechanistic actions. This seminal work significantly advanced the scientific community's understanding of how these potent toxins function at a molecular level, detailing the complex processes involved in their activity. Published in a highly respected journal, their research provided a comprehensive overview that is vital for anyone studying the basic science of neurotoxins, laying groundwork for further investigations into their biological effects and potential applications. The study's depth in explaining the underlying principles of botulinum toxin action makes it a cornerstone reference for researchers.
- Genetic, structural, and mechanistic insights into botulinum neurotoxins.
- Published in Nature Reviews Microbiology, volume 12, issue 8, pages 535-549.
- Accessible via Digital Object Identifier (DOI): 10.1038/nrmicro3295.
What were the major steps in botulinum toxin action identified by Simpson (2004)?
Simpson's 2004 review meticulously outlined the major steps involved in the action of botulinum toxin, providing a clear and comprehensive sequence of events from its entry into the body to its ultimate paralytic effect. This work is fundamental for understanding the pathophysiology of botulism and the therapeutic applications of the toxin. Simpson's detailed analysis clarified how the toxin targets nerve cells, enters them, and then cleaves specific proteins essential for neurotransmitter release, thereby inhibiting muscle contraction. The publication served as a critical reference for pharmacologists and toxicologists, consolidating knowledge on the precise molecular cascade that defines botulinum toxin's potent neurotoxic activity and its clinical implications.
- Detailed major steps in botulinum toxin action and its cellular targets.
- Featured in Annual Review of Pharmacology and Toxicology, volume 44, pages 167-193.
- Identified by Digital Object Identifier (DOI): 10.1146/annurev.pharmtox.44.101802.121554.
How did Pirazzini, Rossetto, Eleopra, & Montecucco (2017) describe botulinum neurotoxin's biology?
Pirazzini, Rossetto, Eleopra, and Montecucco's 2017 review provided an extensive examination of botulinum neurotoxins, encompassing their biology, pharmacology, and toxicology. This comprehensive article synthesized a vast amount of research, offering a holistic view of these complex substances. The authors delved into the biological origins and characteristics of the toxins, their pharmacological effects on the nervous system, and their toxicological profiles, which are crucial for understanding both their harmful potential and their therapeutic utility. This publication is an invaluable resource for researchers and clinicians seeking a broad yet detailed understanding of botulinum neurotoxins from multiple scientific perspectives, highlighting their multifaceted nature and impact.
- Comprehensive review of botulinum neurotoxin's biology, pharmacology, and toxicology.
- Published in Pharmacological Reviews, volume 69, issue 2, pages 127-145.
- Associated with Digital Object Identifier (DOI): 10.1124/pr.
How has botulinum toxin evolved from toxin to treatment, according to Dressler & Saberi (2017)?
Dressler and Saberi's 2017 article traced the remarkable evolution of botulinum toxin from a potent natural toxin to a widely recognized and utilized therapeutic agent. Their work highlighted the transformative journey of this substance, emphasizing how scientific understanding and medical innovation converted a dangerous biological agent into a valuable tool for treating various medical conditions. The authors discussed the historical context, the discovery of its therapeutic potential, and its current applications in neurology, aesthetics, and other fields. This publication provides a compelling narrative of scientific progress, illustrating how detailed research can repurpose harmful substances for beneficial medical outcomes, impacting patient care significantly.
- Explored the transformation of botulinum toxin from a harmful substance to a therapeutic treatment.
- Appeared in Toxins, volume 9, issue 10, article number 327.
- Identified by Digital Object Identifier (DOI): 10.3390/toxins9100327.
What did Montecucco (2018) contribute to understanding Clostridial Neurotoxins?
Montecucco's 2018 work, titled 'Clostridial Neurotoxins: The Molecular Pathogenesis of Botulism and Tetanus,' provided an in-depth exploration of the molecular mechanisms underlying two severe neuroparalytic diseases: botulism and tetanus. This book-length contribution offered a comprehensive analysis of the clostridial neurotoxins responsible for these conditions, detailing their structure, function, and the precise ways they disrupt neuronal signaling. Montecucco's expertise in the field allowed for a thorough examination of the pathogenesis, offering critical insights into how these toxins cause disease and potential avenues for intervention. This publication serves as a definitive reference for understanding the intricate molecular basis of these significant public health threats.
- Focused on Clostridial Neurotoxins: The Molecular Pathogenesis of Botulism and Tetanus.
- Published by Springer, providing a comprehensive book-length treatment of the subject.
Frequently Asked Questions
What is the primary focus of these APA citations?
These citations primarily focus on foundational research concerning botulinum neurotoxins, covering their mechanisms, biological aspects, and therapeutic applications. They provide essential references for understanding the toxin's scientific background and medical relevance.
Why are DOIs important in these citations?
Digital Object Identifiers (DOIs) provide a persistent, unique link to the online version of an article. They ensure that the cited work can be easily located and accessed, which is crucial for academic verification, research reproducibility, and maintaining citation accuracy in scientific literature.
How do these studies collectively advance understanding of botulinum neurotoxins?
These studies collectively advance the understanding of botulinum neurotoxins by detailing their genetic, structural, and mechanistic insights, major steps in action, and evolution from a harmful toxin to a valuable therapeutic treatment. They form a comprehensive knowledge base.
Related Mind Maps
View AllNo Related Mind Maps Found
We couldn't find any related mind maps at the moment. Check back later or explore our other content.
Explore Mind Maps
